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Professor Charles Francis Xavier, who has the mutant ability to read minds, searches for new mutants to train them how to use their powers for good and to prevent the mutants from harming themselves and others at his School for Gifted Youngsters. His opposition, Magneto Master of Magnetism, is doing the same thing, but for evil purposes. He has made Mystique who is a shape-shifter, a principle of his high school to gather evil mutants to prepare them for war against non-mutants. The most interesting plot of the story is that all the heroes and villains attend the same high school. The classic battle of good vs. evil has begun again.
故事發生在1963年，時值冷戰期間，啞女艾麗莎（莎莉·霍金斯 Sally Hawkins 飾）在政府實驗室里工作，是那里的一名清潔女工。年幼時，一場大病奪走了艾麗莎的聲音，之后一直至今，她都在沉默之中過著形單影只的生活，全部的朋友就只有畫家老頭（理查德·詹金斯 Richard Jenkins 飾）和同事塞爾達（奧克塔維亞·斯賓瑟 Octavia Spencer 飾）。 一天，實驗室里拉響了高度戒備的警報，一個神秘的裝滿了水的罐子被送了進來，艾麗莎震驚的發現，罐子里關著一個半人半魚的怪異生物。在理查